Table 2. Interactions at the astacin–fetuin-B interface.
The first residue/atom belongs to fetuin-B and the second to astacin. The overall resolution of the structure is 3.1 Å, the estimated overall average coordinate error is 0.42 Å based on the Luzzati plot, and the dispersion precision indicator based on the free R factor is 0.49 Å. Thus, the distances are approximate.
| Hydrogen bonds |
| Y113 Oη–S62 Oγ, 3.0 Å |
| H151 Nδ1–N127 Oδ1, 3.1 Å |
| T152 O–Y101 Oη, 2.9 Å |
| T153 O–V68 N, 2.7 Å |
| D156 Oδ1–Y149 Oη, 2.7 Å |
| D156 Oδ2–E93 O∊2, 2.9 Å |
| Q199 N∊2–S62 O, 3.1 Å |
| S202 O–Y177 Oη, 3.9 Å |
| S202 O–W158 N∊1, 3.6 Å |
| Y206 Oη–D121 Oδ1, 3.3 Å |
| Ionic interactions |
| D156 Oδ1–Zn999, 2.3 Å |
| D156 Oδ2–Zn999, 2.3 Å |
| Hydrophobic interactions (<4 Å) |
| F112–W65 |
| F112–Y67 |
| C154–W65 |
| P155–V68 |
| P155–H96 |
| P155–H102 |
| D156–W65 |
| C157–W65 |
| P158–W65 |
| N198–M124 |
| Q199–G63 |
| W200–M124 |
| W200–F154 |
| V201–G63 |
| V201–C64 |
| V201–G83 |
| V201–C84 |
| C154–W65 |
| S202–Y177 |
| S245–W158 |