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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: J Allergy Clin Immunol. 2018 Jun 20;143(1):258–265. doi: 10.1016/j.jaci.2018.06.012

FIG 1. IgA deficiency and elevated plasma endotoxin concentrations correlate with AIC development in CVID patients.

FIG 1.

Representative dot plots of IgG and IgA expression on CD19+CD27+ gated memory B cells from the indicated subjects are shown in (A). (B) CD27+IgG+ and CD27+IgA+ B cell frequencies in HD and CVID patients without or with AIC displayed as proportions of total circulating B cells. (C) Serum IgA and (D) plasma endotoxin concentrations are displayed. Dark bars represent average group values. Statistically significant differences are indicated, **P <0.01, ****P <0.0001 (Mann-Whitney U tests).