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. 2016 Aug 20;2016(8):CD010744. doi: 10.1002/14651858.CD010744.pub2

Summary of findings 2. One form of behavioural treatment compared to a different form of behavioural treatment in smokers with COPD.

One form of behavioural treatment compared to a different form of behavioural treatment in smokers with COPD
Patient or population: smokers with COPD
 Settings: in‐ and outpatients
 Intervention: one form of behavioural treatment
 Comparison: a different form of behavioural treatment
Outcomes Illustrative comparative risks* (95% CI) Relative effect
 (95% CI) No of Participants
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
A different form of behavioural treatment One form of behavioural treatment
Prolonged abstinence at longest follow‐up
 Follow‐up: 6 to 12 months See comment See comment Not estimable 739
 (4 studies) See comment No pooling due to clinical and statistical heterogeneity. Individual RR were 2.18 (1.05, 4.49), RR 0.97 (0.47, 1.99), RR 1.09 (0.59, 2.04), and RR not estimable. 3 of the 4 studies had a low risk of bias. 1 study had a high risk of bias due to poor adherence to the study protocol
Point prevalence abstinence at longest follow‐up
 Follow‐up: 6 to 12 months See comment See comment Not estimable 500
 (3 studies) See comment No pooling due to clinical and statistical heterogeneity. Individual RR were 1.67 (0.68, 4.11), RR 1.35 (0.80, 2.28), and RR 0.15 (0.01, 2.83). 1 study had a low risk of bias, 1 study had a high risk of bias due to participants' poor adherence to the study protocol, and the remaining study had an unclear risk of bias
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: confidence interval; COPD: chronic obstructive pulmonary disease; RR: risk ratio
GRADE Working Group grades of evidence
 High quality: Further research is very unlikely to change our confidence in the estimate of effect.
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
 Very low quality: We are very uncertain about the estimate.