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. 2018 Dec 18;141(1):98–103. doi: 10.1021/jacs.8b11466

Table 1. Optimization for Cobalt-Catalyzed Amination Using Anthranils (2a)a.

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entry [met] (10 mol %) yield (%)b
1 CoCl2 65
2 MnCl2 0
3 CrCl2 0
4 FeCl2 0
5 Fe(acac)3 0
6 – 0
7 CoCl2 0c
a

Reaction conditions: 4a (0.75 mmol), 2a (0.50 mmol), [cat.] (10 mol %), THF (2.0 mL), 23 °C, N2, 16 h.

b

Isolated yields.

c

PhMgCl (1.5 equiv) was used.