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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: J Bone Miner Res. 2018 Jun 22;33(10):1760–1772. doi: 10.1002/jbmr.3473

Figure 3.

Figure 3.

Femurs of sActRIIB-mFc treated female WT and male and female +/G610C mice exhibited increased periosteal bone formation rate. A) Representative fluorochrome labeled cortical cross-sectional images of female mice. B) periosteal mineralized surface per bone surface (Ps.MS/BS), C) endocortical mineralized surface per bone surface (Ec.MS/BS), D) periosteal mineral apposition rate (Ps.MAR), E) endocortical mineral apposition rate (Ec.MAR), F) periosteal bone formation rate per bone surface (Ps.BFR/BS), and G) endocortical bone formation rate per bone surface (Ec.BFR/BS) of male and female WT, +/G610C, and oim/oim vehicle (solid color) and sActRIIB-mFc (diagonal) treated mice. (WT [blue], +/G610C [red], and oim/oim [green]). (n) is indicated for each genotype and treatment, the number of samples are lower in +/G610C and oim/oim due to section fragility and limited number of callus free femurs. Values are MEAN±SD. *p<0.05; †p<0.05 vs. WT+vehicle treated mice.