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. 2019 Mar 4;151(3):292–315. doi: 10.1085/jgp.201812213

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© 2019 Tilley et al.

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Figure 3. — Saturating GxTx increases Kv2.1 activation sigmoidicity in whole-cell recordings. (A) Values of σ from fits of Eq. 3 and in Fig. 2 A. Symbols denote individual cells. (B) Geometric mean of σ from cells in A. Black circles, control; pink triangles, 10 nM GxTx; red inverted triangles, 100 nM; dark red diamonds, 1 µM. (C) Activation curves calculated from Eq. 3 when σ is varied.