Table 1. Rate constants for Models FR and FRT with and without GxTx.
Model | Condition | Rate constant | k0mV/s−1 | z/e0 |
---|---|---|---|---|
FR | Control | α | 240 | 0.65 |
β | 110 | 0.17 | ||
GxTx | α | 17 | 0.73 | |
β | 10 | 0.50 | ||
FRT | GxTx | ktr | 38 | 0.93 |
kre | 8.7 | 1.0 | ||
FR, FRT | Control, GxTx | kopen | 160 | 0 |
kclose | 38 | 0 |
Best fit of voltage-dependent rate constants to the simulations presented in Figs. 11 and 12. Values of α, β, ktrap, and krelease are from fits of Eq. 8 shown in Fig. 11, D and E; and Fig. 12 C. Values of kopen, and kclose were chosen as described in Results. The k0mV column gives the rate at 0 mV for each rate constant, and the z column indicates the equivalent electronic charge assigned to the rate constant.