Table 1. Summary of targeting neurons, microglia, oligodendrocytes, and astrocytes using rAAVs in BSCs.
BSC cell type | Promoter | Capsid |
---|---|---|
Non-specific | hCBA | 2/1, 2/2, 2/6, 2/8, 2/9 |
Microglia | CD68 | 2/6 with three mutations, Y731F/Y705F/T492V (TM6) |
Neurons | CamKII, MAP-2 | 2/6, 2/8 |
Oligodendrocytes | MBP | 2/8 |
Astrocytes | GFAP | 2/8 |