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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: JAMA Psychiatry. 2019 Jan 1;76(1):87–94. doi: 10.1001/jamapsychiatry.2018.2546

Table 1.

Model Estimates for Associations Between Cannabis Involvement and PLEsa

Frequent Cannabis Use CUD Current Cannabis Use
β lower
CI
upper
CI
t p β lower
CI
upper
CI
t p β lower
CI
upper
CI
t p
Sexb −0.02 −0.05 0.01 −1.08 .28 −0.01 −0.04 0.01 −0.91 .36 −0.02 −0.05 0.01 −1.32 .19
Age −0.04 −0.07 −0.01 −2.52 .01 −0.04 −0.07 −0.01 −2.51 .01 −0.04 −0.07 −0.01 −2.27 .02
MZ −0.06 −0.10 −0.02 −3.24 .001 −0.06 −0.10 −0.02 −3.17 .002 −0.06 −0.10 −0.02 −3.02 .003
DZ −0.07 −0.11 −0.03 −3.39 .001 −0.07 −0.11 −0.03 −3.33 .001 −0.06 −0.10 −0.02 −3.10 .002
Samplec 0.03 −0.01 0.07 1.66 .10 0.02 −0.02 0.06 1.11 .27 0.02 −0.01 0.06 1.23 .22
Household Income −0.15 −0.18 −0.12 −9.28 <.001 −0.15 −0.18 −0.12 −9.56 <.001 −0.15 −0.18 −0.12 −9.57 <.001
Lifetime Smoking 0.03 0.00 0.06 1.88 .06 0.03 0.00 0.06 1.97 .049 0.05 0.02 0.08 3.06 .002
Lifetime Drinking 0.01 −0.02 0.04 0.89 .37 0.01 −0.02 0.04 0.79 .43 0.02 −0.01 0.05 1.17 .24
Lifetime Other Illicit Drug Use 0.09 0.06 0.13 5.81 <.001 0.09 0.06 0.12 5.60 <.001 0.11 0.08 0.14 6.75 <.001
Cannabis Involvement Variable 0.11 0.08 0.14 6.71 <.001 0.13 0.09 0.16 7.89 <.001 0.07 0.04 0.10 4.73 <.001

Abbreviations: β=standardized regression coefficient; CI=95% bootstrapped (5000 iterations) Confidence Interval; t=t-test test statistic; p=p-value; CUD=cannabis abuse/dependence; MZ=monozygotic; DZ=dizygotic.

a

Significant model estimates are in bold.

b

Female as reference group for sex.

c

Australian Twin Registry as reference group for sample.