Table 5.
Comparison of clinicopathological characteristics between early pure and mixed signet-ring cell gastric carcinoma
| Clinicopathologic Feature | Mixed SRCC | Pure SRCC | P value |
|---|---|---|---|
| Age (year) | |||
| mean±SD | 54.8±12.0 | 51.3±13.0 | NS |
| median(range) | 54(20-69) | 51.5(27-69) | |
| Gender | |||
| Male | 60(74.1) | 33(41.8) | <0.0001 |
| Female | 21(25.9) | 46(58.2) | |
| Location | |||
| cardia | 7(8.6) | 4(5.1) | NS |
| body | 28(34.6) | 23(29.1) | |
| angularis | 9(11.1) | 10(12.7) | |
| antrum | 32(39.5) | 32(40.5) | |
| pylorus | 5(6.2) | 10(12.7) | |
| Gross pattern | |||
| 0-I | 1(1.2) | 2(2.5) | < 0.05 |
| O-2a | 10(12.3) | 9(11.4) | |
| O-2b | 12(14.8) | 21(26.6) | |
| O-2c | 16(19.8) | 24(30.4) | |
| O-3 | 42(51.9) | 23(29.1) | |
| Tumor size(cm) | |||
| mean±SD | 2.5±1.3 | 2.3±1.6 | NS |
| median(range) | 2.2(0.4-3.5) | 2(0.2-6.5) | |
| Invasion depth | |||
| M | 42(51.8) | 51(64.5) | NS |
| SM | 39(48.2) | 28(35.5) | |
| Lymphovascular invasion | |||
| Absence | 67(82.7) | 77(97.5) | < 0.01 |
| Presence | 14(17.3) | 2(2.5) | |
| Hp infection | |||
| Absence | 35(43.2) | 53(67.1) | < 0.01 |
| Presence | 46(56.8) | 26(32.9) | |
| Atrophic gastritis | |||
| Absence | 34(42.0) | 39(49.4) | NS |
| Presence | 47(58.0) | 40(50.6) | |
| Lymph node metastasis | |||
| Absence | 59(72.8) | 68(86.1) | NS |
| Presence | 22(27.2) | 11(13.9) | |
| Ulcer finding | |||
| Absence | 33(40.7) | 35(44.3) | NS |
| Presence | 48(59.3) | 44(55.7) |
NS: not significant; SD: standard deviation; Hp: helicobacter pylori; M: intramucosal; SM: submucosal invasion.