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. 2019 Mar 6;39(3):BSR20180226. doi: 10.1042/BSR20180226

Figure 2. LncRNA-MALAT1 promoted angiogenesis of mouse BMECs under OGD conditions.

Figure 2

(A) qRT-PCR test of stable lncRNA-MALAT1 overexpression in pcDNA-MALAT1 group and lncRNA-MALAT1 knockdown in si-MALAT1 group. (B) The results of tubule formation in groups mentioned in (A) were expressed as relative tube length. (C) Migration of BMECs was measured by Transwell migration assay and presented in the form of number of migration cells. (D) The effects of lncRNA-MALAT1 on tube formation in BMECs was measured by Matrigel assay. (E) The results of migrated BMECs under OGD stimulation were expressed as the number of migrated cells per field (magnification: ×200; scale bar: 100 μm). BMECs were treated under OGD conditions for 12 h, grouping as OGD(−), OGD(12 h), si-control, si-MALAT1, pcDNA-control, and pcDNA-MALAT1. Data represent means ± S.D. based on three independent experiments; *P<0.05, **P<0.01.