Table 5.
Cox hazard regression models for overall survival (OS) and recurrence-free survival (RFS)
| OS | RFS | |||||||
|---|---|---|---|---|---|---|---|---|
| HR | 95%CI | P-value | HR | 95%CI | P-value | |||
| RR | ||||||||
| Stage | I to IV (Incremental) | 2.22 | 1.30-3.80 | 0.004 | 2.13 | 1.15-3.93 | 0.016 | |
| Margin | Positive (vs. Negative/close) | 2.72 | 1.42-5.21 | 0.003 | ||||
| PD-L1 | High (vs. Low) | 1.33 | 1.07-1.66 | 0.010 | 1.23 | 0.98-1.54 | 0.077 | |
| RS | ||||||||
| P16 | Positive (vs. Negative) | 0.02 | 0.00-18.98 | 0.261 | ||||
| Overall | ||||||||
| Stage | I to IV (Incremental) | 1.80 | 1.19-2.72 | 0.005 | 1.63 | 1.05-2.51 | 0.029 | |
| Margin | Positive (vs. Negative/close) | 2.27 | 1.33-3.87 | 0.003 | ||||
| PD-1 | High (vs. Low) | 0.97 | 0.78-1.21 | 0.795 | ||||
| Radiosensitivity | RR (vs. RS) | 1.76 | 1.09-2.85 | 0.021 | 1.43 | 0.70-2.91 | 0.330 |
Abbreviations: HPV, HPV status assessed by ISH testing; P16, HPV status assessed by p16 testing; RR, radioresistant group; RS, radiosensitive group.