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. 2019 Jan 30;10(4):799–809. doi: 10.7150/jca.29643

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Fig 4 — Meta-analysis of subgroup. (A) Subgroup of first line of treatment on PFS between VEGFR-TKIs and chemotherapy: fixed-effects model. (B) Subgroup of second line of treatment on PFS between VEGFR-TKIs and chemotherapy: fixed-effects model. (C) Subgroup of first line of treatment on OS between VEGFR-TKIs and chemotherapy: fixed-effects model. (D) Subgroup of second line of treatment on OS between VEGFR-TKIs and chemotherapy: fixed-effects model. (E) Subgroup of first line of treatment on ORR between VEGFR-TKIs and chemotherapy: fixed-effects model. (F) Subgroup of second line of treatment on ORR between VEGFR-TKIs and chemotherapy: fixed-effects model. (G) Subgroup of first line of treatment on DCR between VEGFR-TKIs and chemotherapy: random-effects model. (H) Subgroup of second line of treatment on DCR between VEGFR-TKIs and chemotherapy: random-effects model.