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. 2019 Jan 29;10(4):1004–1012. doi: 10.7150/jca.26277

Figure 3.

Figure 3

PI3K/Akt signaling is involved in release of TNF-α and IL-6 induced by the FGFR1 and TLR4 agonists. The A549, PC-9 and SK-MES-1 (n=3) cells were respectively treated with culture medium, 1ug/ml LPS or 10ng/ml bFGF, 10µM LY294002 with or without LPS or bFGF. A:the expression of TNF-α was measured by ELISA(Mean ± SD). B: the expression of IL-6 was measured by ELISA (Mean ± SD). *p < 0.05 vs the control group, **p < 0.01 vs the control group, #p < 0.05 vs the LPS group, ##p < 0.01 vs the LPS group, &p < 0.05 vs the bFGF group, &&p < 0.01 vs the bFGF group.