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. 2019 Feb 27;13:68. doi: 10.3389/fncel.2019.00068

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Copyright © 2019 Yang, Chen, Zhao, Luo, Xu, Du, Wang, Li, Yang, Hu, Zhang, Li, Xia, Chen, Ma, Tian and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of COX2 inhibitor on changes of hippocampus and cortex PGD2 content in T2DM rat cortex and hippocampus. Compared with that of normal group, the contents of PGD2 significantly increased in model group. Compared with that of model group, the administration of COX2 inhibitor significantly decreased the content of PGD2. Data are expressed as the mean ± SD for six individual rats in each group, and were analyzed statistically using one-way ANOVA, followed by post hoc Tukey’s test. ^∗∗P < 0.01 compared with normal group. ^##P < 0.01 compared with model group, respectively.