Skip to main content
. 2019 Feb 27;10:141. doi: 10.3389/fphys.2019.00141

Figure 1.

Figure 1

Schematic depicting the Connexin 43 (Cx43) gap junction and hemichannel and pannexin 1 (Px1) channel. A connexon consists of six connexin subunits. A Cx43 gap junction is made up of two opposing connexons, each contributed from two adjacent cells. A Cx43 hemichannel is an unopposed connexon. A Px1 channel is formed by six pannexin subunits. Px1 does not form gap junctions due to N-linked glycosylation on the extracellular loop.