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. 2019 Mar 5;9:3596. doi: 10.1038/s41598-019-40471-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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RoxP can protect human cells from oxidative damage in vitro. Human monocyte (A) or keratinocyte (B) cell lines were exposed to oxidative stress through addition of paraquat, while adding RoxP momentarily afterwards. Cells were incubated for 24 h (keratinocytes) or 48 h (monocytes) before cell viability was analyzed through MTT assays. Representative microscopy visualizations of monocytes after paraquat (C) or paraquat + RoxP (D) are demonstrated. Statistics were calculated using a student’s t-test.