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. 2019 Mar 5;9:3469. doi: 10.1038/s41598-019-39830-x

Table 4.

Multivariate analysis of risk factors for the development and recurrence of benign paroxysmal positional vertigo during the follow-up period in the whole cohort.

Overall development of BPPV (N = 355,594) Overall recurrence of BPPV (N = 7,765)
Crude HR (95% CI) Adjusted HR (95% CI) Crude HR (95% CI) Adjusted HR (95% CI)
Osteoporosis
   No 1 1 1 1
   Yes 1.75 (1.67–1.83) 1.76 (1.68–1.84) 1.12 (0.998–1.26) 1.12 (1.001–1.26)
Gender
   Male 1 1 1 1
   Female 1.60 (1.44–1.77) 1.54 (1.38–1.70) 1.10 (0.84–1.44) 1.07 (0.82–1.40)
Age
   <65 1 1 1 1
   ≥65 0.81 (0.77–0.85) 0.80 (0.76–0.84) 0.93 (0.83–1.04) 0.92 (0.82–1.04)
Income
   Lowest 1 1 1 1
   Lower mid 1.12 (1.04–1.21) 1.08 (1.00–1.16) 0.77 (0.63–0.93) 0.75 (0.62–0.92)
   Upper mid 1.18 (1.10–1.26) 1.15 (1.07–1.23) 0.96 (0.82–1.13) 0.95 (0.81–1.12)
   Highest 1.20 (1.13–1.27) 1.20 (1.13–1.27) 0.92 (0.80–1.06) 0.93 (0.81–1.07)
Urbanized level
   Metro polis 1 1 1 1
   Urban 0.80 (0.76–0.83) 0.81 (0.77–0.85) 0.95 (0.85–1.06) 0.95 (0.85–1.06)
   Rural area 0.57 (0.52–0.63) 0.61 (0.55–0.67) 0.85 (0.67–1.08) 0.84 (0.66–1.07)
Hypertension
   No 1 1 1 1
   Yes 1.05 (1.00–1.10)* 1.13 (1.07–1.19) 0.97 (0.87–1.08) 0.99 (0.88–1.11)
Diabetes mellitus
   No 1 1 1 1
   Yes 1.02 (0.95–1.11) 1.00 (0.92–1.08) 0.95 (0.78–1.16) 0.97 (0.79–1.19)