Figure 5.

Characterization of CcdB using NMR. 2D ¹⁵N-¹H HSQC spectra of CcdB acquired at pH 4 (red color) and at pH 7 (black color) are shown. Crosspeaks are well dispersed at both pH values, suggesting that CcdB is in a globular state under both conditions. Several crosspeaks undergo a shift upon change of pH from 7 to 4, likely because of pH-induced structural changes. To see this figure in color, go online.