Table 1.
Baseline (1987–1989) demographic and clinical characteristics of 6,594 men in the ARIC study, by current aspirin and NA-NSAID use at Visit 1
Aspirin Use | NA-NSAID Use | |||
---|---|---|---|---|
No | Yes | No | Yes | |
N | 4743 | 1851 | 5718 | 876 |
Age (years), mean (sd) | 54.3 (5.8) | 54.9 (5.6) | 54.4 (5.8) | 55.0 (5.8) |
BMI (kg/m2), mean (sd) | 27.4 (4.2) | 27.8 (4.3) | 27.4 (4.2) | 28.4 (4.6) |
Race, n (%) | ||||
White | 3403 (72) | 1675 (90) | 4340 (76) | 720 (82) |
Black | 1340 (28) | 194 (10) | 1378 (24) | 156 (18) |
Center, n (%) | ||||
Forsyth | 1207 (25) | 524 (28) | 1477 (26) | 254 (29) |
Jackson | 1188 (25) | 153 (8) | 1459 (26) | 261 (30) |
Minneapolis | 1136 (24) | 666 (36) | 1219 (21) | 122 (14) |
Washington County | 1212 (26) | 508 (27) | 1563 (27) | 239 (27) |
Cigarette Smoking Status, n (%) | ||||
Current/Recent (quit <10 years ago) | 2084 (44) | 810 (44) | 2523 (44) | 371 (42) |
Former (quit ≥10 years ago) | 1285 (27) | 572 (31) | 1570 (27) | 287 (33) |
Never | 1374 (29) | 469 (25) | 1625 (28) | 218 (25) |
Education, n (%) | ||||
Basic | 1242 (26) | 356 (19) | 1371 (24) | 277 (26) |
Intermediate | 1734 (37) | 659 (36) | 2059 (36) | 334 (38) |
Advanced | 1756 (37) | 834 (45) | 2275 (40) | 315 (36) |
Missing | 11 (0) | 2 (0) | 13 (0) | 0 (0) |
Family History of PCaa, n (%) | ||||
Yes | 275 (6) | 100 (5) | 319 (6) | 56 (6) |
No | 4121 (87) | 1608 (87) | 4977 (87) | 752 (86) |
Missing | 347 (7) | 143 (8) | 422 (7) | 68 (8) |
Statin Useb, n (%) | ||||
Yes | 17 (0) | 20 (1) | 29 (1) | 8 (1) |
No | 4726 (100) | 1831 (99) | 5689 (99) | 868 (99) |
Prevalent CHD, n (%) | ||||
Yes | 209 (4) | 322 (17) | 441 (8) | 90 (10) |
No | 4431 (93) | 1501 (81) | 5163 (90) | 769 (88) |
Missing | 103 (2) | 28 (2) | 114 (2) | 17 (2) |
Diabetes, n (%) | ||||
Diagnosed diabetes | 342 (7) | 138 (7) | 401 (7) | 79 (9) |
Undiagnosed diabetes | 213 (4) | 80 (4) | 245 (4) | 48 (5) |
Prediabetes | 1790 (38) | 809 (44) | 2246 (39) | 353 (40) |
No diabetes | 2391 (50) | 824 (45) | 2822 (49) | 393 (45) |
Missing | 4 (0) | 3 (0) | ||
Frequency of Routine Physical Examinations | ||||
≥Once every 5 years | 2779 (59) | 1230 (66) | 3405 (60) | 604 (69) |
<Once every 5 years | 1949 (41) | 620 (34) | 2299 (40) | 270 (31) |
Missing | 15 (0) | 1 (0) | 14 (0) | 2 (0) |
Abbreviations: ARIC, Atherosclerosis Risk in Communities; NA-NSAID, non-aspirin nonsteroidal anti-inflammatory drug; sd, standard deviation; BMI, body mass index; PCa, prostate cancer; CHD, coronary heart disease
Reported at Visit 3
Statin use is low at baseline because the first statin was not FDA approved until 1987