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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Psychopharmacology (Berl). 2018 Nov 10;236(2):671–684. doi: 10.1007/s00213-018-5093-3

Fig. 3.

Fig. 3.

Chronic subcutaneous THC and voluntary alcohol consumption, alone or when combined, differently affected caloric intake and weight gain (Experiment 1a: EtOH, n = 8; CTL, THC, & COM, n = 10/group). (A) EtOH & COM rats consumed similar doses of sweetened 10% alcohol. (B) Blood ethanol concentration (BEC) correlated with 1-h alcohol intake in the EtOH group. (C) BEC correlated with 3-h alcohol intake in the EtOH group, and with 3-h alcohol intake in the COM group after subcutaneous 10 mg/kg THC. (D) THC injection dose-dependently stimulated 3-h chow intake. Alcohol consumption reduced 3-h chow intake and blunted the hyperphagic effect of THC. THC vs. EtOH & COM: *p < 0.004; CTL vs. EtOH & THC: #p < 0.03.