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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Biochim Biophys Acta Gene Regul Mech. 2018 Oct 5;1862(3):382–393. doi: 10.1016/j.bbagrm.2018.09.010

Figure 5: Post-transcriptional regulation of gene expression by miRNA.

Figure 5:

(A) Downregulation of METTL14 in hepatocellular carcinoma (HCC) cells leads to an increase in unprocessed pri-miR-126. Mature miR-126 is associated with metastasis. (B) In HCC cells, lower expression of miR-145 allows for expression of YTHDF2 protein, decreasing the levels of m6A in cells, and increasing cellular proliferation.