Table 1.
Comparison of baseline demographic, clinical, radiologic, and treatment characteristics between ICH patients who underwent nonoperative management versus surgical intervention.
| Variable | Nonoperative Management (n=2,658) | Surgical Intervention (n=289) | p-value |
|---|---|---|---|
| Age, mean yr (SD) | 62.1 (14) | 57.1 (13.4) | <0.001 |
| Male sex, n (%) | 1,550/2,658 (58.3) | 183/289 (63.3) | 0.100 |
| Race/Ethnicity, n (%) | <0.001 | ||
| White | 890/2,658 (33.5) | 86/289 (29.8) | |
| Black | 920/2,658 (34.6) | 69/289 (23.9) | |
| Hispanic | 848/2,658 (31.9) | 134/289 (46.4) | |
| Baseline mRS, n (%) | <0.001 | ||
| 0 | 1,837/2,648 (69.4) | 238/288 (82.6) | |
| 1 | 317/2,648 (12) | 22/288 (7.6) | |
| 2 | 267/2,648 (10.1) | 16/288 (5.6) | |
| 3 | 134/2,648 (5.1) | 6/288 (2.1) | |
| 4 | 77/2,648 (2.9) | 4/288 (1.4) | |
| 5 | 16/2,648 (0.6) | 2/288 (0.7) | |
| Admission GCS, median (IQR) | 15 (11–15) | 13 (8–15) | <0.001 |
| Antiplatelet use, n (%) | 1,166/2,631 (44.3) | 116/285 (40.7) | 0.243 |
| Anticoagulant use, n (%) | 261/2,621 (10) | 34/283 (12) | 0.277 |
| INR, mean (SD) | 1.2 (0.8) | 1.3 (0.8) | 0.147 |
| PTT, mean sec (SD) | 29.5 (8.4) | 29.5 (6.6) | 0.983 |
| Platelet count, mean k/uL (SD) | 225.4 (75.9) | 224.9 (82.5) | 0.921 |
| ICH volume, mean cm3 (SD) | 18.2 (23.4) | 46.2 (29.3) | <0.001 |
| Infratentorial ICH location, n (%) | 326/2,658 (12.3) | 67/289 (23.2) | <0.001 |
| Lobar ICH location, n (%) | 802/2,658 (30.2) | 130/289 (45) | <0.001 |
| Presence of IVH, n (%) | 1,057/2,594 (40.8) | 126/262 (48.1) | 0.021 |
| ICP monitoring, n (%) | 398/2,658 (15) | 149/289 (51.6) | <0.001 |
| Mannitol use, n (%) | 335/2,654 (12.6) | 142/289 (49.1) | <0.001 |
| Hypertonic saline use, n (%) | 78/2,658 (2.9) | 29/289 (10) | <0.001 |
n = number; yr = year; uL = microliter; k = ×1,000; ICH = intracerebral hemorrhage; IVH = intraventricular hemorrhage; GCS = Glasgow Coma Scale; IQR = interquartile range; mRS = modified Rankin Scale; ICP = intracranial pressure; INR = international normalized ratio; PTT = partial thromboplastin time.