Table 3.
Comparison of baseline demographic, clinical, radiologic, and treatment characteristics between patients with supratentorial ICH who underwent nonoperative management versus surgical intervention.
| Variable | Nonoperative Management (n=2,332) | Surgical Intervention (n=222) | p-value |
|---|---|---|---|
| Age, mean yr (SD) | 62.3 (14) | 55.7 (13.5) | <0.001 |
| Male sex, n (%) | 1,367/2,332 (58.6) | 140/222 (63.1) | 0.198 |
| Race/Ethnicity, n (%) | <0.001 | ||
| White | 797/2,332 (34.2) | 68/222 (30.6) | |
| Black | 804/2,332 (34.5) | 49/222 (22.1) | |
| Hispanic | 731/2,332 (31.4) | 105/222 (47.3) | |
| Baseline mRS, n (%) | <0.001 | ||
| 0 | 1,611/2,322 (69.4) | 185/222 (83.3) | |
| 1 | 285/2,322 (12.3) | 19/222 (8.6) | |
| 2 | 231/2,322 (10) | 10/222 (4.5) | |
| 3 | 118/2,322 (5.1) | 3/222 (1.4) | |
| 4 | 64/2,322 (2.8) | 3/222 (1.4) | |
| 5 | 13/2,322 (0.6) | 2/222 (0.9) | |
| Admission GCS, median (IQR) | 15 (12–15) | 12 (8–15) | <0.001 |
| Antiplatelet use, n (%) | 1,030/2,307 (44.7) | 91/219 (41.6) | 0.378 |
| Anticoagulant use, n (%) | 216/2,298 (9.4) | 22/218 (10.1) | 0.739 |
| INR, mean (SD) | 1.2 (0.8) | 1.2 (0.6) | 0.874 |
| PTT, mean sec (SD) | 29.5 (8.6) | 29.1 (5.9) | 0.535 |
| Platelet count, mean k/uL (SD) | 225.3 (76.3) | 226.6 (87.5) | 0.811 |
| ICH volume, mean cm3 (SD) | 19.7 (24.4) | 53.5 (29) | <0.001 |
| Lobar ICH location, n (%) | 802/2,332 (34.4) | 130/222 (58.6) | <0.001 |
| Presence of IVH, n (%) | 961/2,278 (42.2) | 96/203 (47.3) | 0.159 |
| ICP monitoring, n (%) | 353/2,332 (15.1) | 108/222 (48.7) | <0.001 |
| Mannitol use, n (%) | 299/2,328 (12.8) | 108/222 (48.7) | <0.001 |
| Hypertonic saline use, n (%) | 75/2,327 (3.2) | 23/222 (10.4) | <0.001 |
n = number; yr = year; uL = microliter; k = ×1,000; ICH = intracerebral hemorrhage; IVH = intraventricular hemorrhage; GCS = Glasgow Coma Scale; IQR = interquartile range; mRS = modified Rankin Scale; ICP = intracranial pressure; INR = international normalized ratio; PTT = partial thromboplastin time.