Table 5.
Comparison of baseline demographic, clinical, radiologic, and treatment characteristics between patients with infratentorial ICH who underwent nonoperative management versus surgical intervention.
| Variable | Nonoperative Management (n=326) | Surgical Intervention (n=67) | p-value |
|---|---|---|---|
| Age, mean yr (SD) | 60.9 (14) | 61.6 (11.7) | 0.700 |
| Male sex, n (%) | 183/326 (56.1) | 43/67 (64.2) | 0.225 |
| Race/Ethnicity, n (%) | 0.497 | ||
| White | 93/326 (28.5) | 18/67 (26.9) | |
| Black | 116/326 (35.6) | 20/67 (29.9) | |
| Hispanic | 117/326 (35.9) | 29/67 (43.3) | |
| Baseline mRS, n (%) | 0.626 | ||
| 0 | 226/326 (69.3) | 53/66 (80.3) | |
| 1 | 32/326 (9.8) | 3/66 (4.6) | |
| 2 | 36/326 (11) | 6/66 (9.1) | |
| 3 | 16/326 (4.9) | 3/66 (4.6) | |
| 4 | 13/326 (4) | 1/66 (1.5) | |
| 5 | 3/326 (0.9) | 0/66 (0) | |
| Admission GCS, median (IQR) | 15 (10.5–15) | 14 (9–15) | 0.271 |
| Antiplatelet use, n (%) | 136/324 (42) | 25/66 (37.9) | 0.538 |
| Anticoagulant use, n (%) | 45/323 (13.9) | 12/65 (18.5) | 0.347 |
| INR, mean (SD) | 1.2 (0.7) | 1.5 (1.2) | 0.020 |
| PTT, mean sec (SD) | 29.1 (6) | 30.6 (8.4) | 0.098 |
| Platelet count, mean k/uL (SD) | 225.7 (72.9) | 219.2 (63.8) | 0.502 |
| ICH volume, mean cm3 (SD) | 8 (9.5) | 21.2 (10.3) | <0.001 |
| Presence of IVH, n (%) | 96/316 (30.4) | 30/59 (50.9) | 0.002 |
| ICP monitoring, n (%) | 45/326 (13.8) | 41/67 (61.2) | <0.001 |
| Mannitol use, n (%) | 36/326 (11) | 34/67 (50.8) | <0.001 |
| Hypertonic saline use, n (%) | 3/326 (0.9) | 6/67 (9) | 0.001 |
n = number; yr = year; uL = microliter; k = ×1,000; ICH = intracerebral hemorrhage; IVH = intraventricular hemorrhage; GCS = Glasgow Coma Scale; IQR = interquartile range; mRS = modified Rankin Scale; ICP = intracranial pressure; INR = international normalized ratio; PTT = partial thromboplastin time.