Distribution of negative outcomes based on peak measured TN-I. A persistent TN-I rise beyond 8 hours after surgery is significantly associated with postoperative hypoperfusion injury and mortality, independent of patient age, ventricular anatomy, complexity of surgery, and level of postoperative support. Examples of hypoperfusion injuries include necrotizing enterocolitis (NEC), neurological injury, renal failure, and pancreatitis. Abbreviations as in Figure 2.