Table 2:

Risk factors for overall survival and neutrophil recovery

Overall Survival		N	N-event	HR (95% CI)	p
	Total	424	164
Registry	EBMT	246	88
	CIBMTR	178	76	0.98 (0.71 – 1.36)	0.918
Age	50–64	354	132
	>=65	70	32	1.21 (0.81 – 1.81)	0.343
Patient sex	Male	216	88
	Female	208	76	0.82 (0.6 – 1.12)	0.205
Performance score	<90%	189	83
	90–100%	235	81	0.71 (0.52 – 0.97)	0.03
GvHD prophylaxis	CNI + MMF	99	39
	CNI + MTX	223	91	1.22 (0.82 – 1.81)	0.319
	Other	102	34	0.86 (0.54 – 1.38)	0.537
Donor	Identical sibling	221	78
	Unrelated donor	203	86	1.47 (1 – 2.16)	0.05
Regimen	non-TBI regimen	321	122
	TBI regimen	103	42	0.76 (0.49 – 1.19)	0.226
Graft source	Bone marrow	229	90
	Peripheral blood	195	74	0.96 (0.7 – 1.32)	0.813
Interval diag-Tx (yrs)		424		0.99 (0.94 – 1.05)	0.818
Neutrophil recovery		N	N-event	sHR (95% CI)	p
	Total	406	368
Registry	EBMT	232	210
	CIBMTR	174	158	1.32 (1.06 – 1.65)	0.014
Age	50–64	337	307
	>=65	69	61	0.95 (0.7 – 1.3)	0.76
Performance score	<90%	181	158
	90–100%	225	210	1.24 (0.99 – 1.54)	0.062
Patient CMV	negative	114	105
	positive	292	263	1.13 (0.91 – 1.41)	0.27
GvHD prophylaxis	CNI + MMF	98	92
	CNI + MTX	210	188	0.59 (0.44 – 0.8)	<0.001
	Other	98	88	0.78 (0.55 – 1.1)	0.15
HSCT period	2005–2009	133	119
	2010–2014	273	249	1.14 (0.89 – 1.45)	0.29
Donor	Identical sibling	210	189
	Unrelated donor	196	179	0.99 (0.79 – 1.24)	0.92
Graft source	Bone marrow	223	199
	Peripheral blood	183	169	1.74 (1.38 – 2.2)	<0.001