(A) 320 J/cm2 LED-RL increased transcription of Let-7a, miRNA-29, miRNA-196a in human skin fibroblasts as measured by microRNA expression analysis. Fold changes were: Let-7a = 2.21, miRNA-29 = 2.11, miRNA-196a = 1.76. Bars represent fold change compared to matched control. (B) 640 J/cm2 LED-RL increased transcription of Let-7a, miRNA-29, miRNA-196a in human skin fibroblasts as measured by microRNA expression analysis. Fold changes were: Let-7a = 1.10, miRNA-29 = 2.04, miRNA-196a = 1.31. Bars represent fold change compared to matched control.