(A) 320 J/cm2 LED-RL decreased transcription of miRNA-21, miRNA-23b, miRNA-31 in human skin fibroblasts as measured by microRNA expression analysis. Fold changes were: miRNA-21 = 0.66, miRNA-23b = 0.89, miRNA-31 = 0.21. Bars represent fold change compared to matched control. (B) 640 J/cm2 LED-RL decreased transcription of miRNA-21, miRNA-23b, miRNA-31 in human skin fibroblasts as measured by microRNA expression analysis. Fold changes were: miRNA-21 = 0.87, miRNA-23b = 0.91, miRNA-31 = 0.64. Bars represent fold change compared to matched control.