Table 4.
Summary of Appendix Tables 10–17, which address two proteins at a time for the early epoch (4a) and separately for the late epoch (4b).a
4a. early epoch | ||||||||||||
TNF-α | IL-8 | ICAM-1 | ||||||||||
Proteins | W | I | S | E | W | I | S | E | W | I | S | E |
IL-6R | V | V | V | V | V | V | ||||||
MMP-9 | V | Λ | V | Λ | V | |||||||
RANTES | V | V | V | V | V | V | ||||||
EPO | Λ | Λ | Λ | Λ | ||||||||
NT-4 | V | V | V | V | ||||||||
BDNF | V | V | V | V | V | V | ||||||
bFGF | Λ | V | V | V | V | |||||||
IGF-1 | V | V | V | V | V | |||||||
VEGF | V | V | V | V | V | V | V | V | ||||
VEGF-R1 | V | V | V | V | V | V | V | V | ||||
VEGF-R2 | V | V | V | V | V | |||||||
PIGF | V | V | V | V | V | V | V | |||||
Ang-1 | V | V | V | V | V | V | V | V | ||||
Ang-2 | ||||||||||||
4b. late epoch | ||||||||||||
TNF-α | IL-8 | ICAM-1 | ||||||||||
Proteins | W | I | S | E | W | I | S | E | W | I | S | E |
IL-6R | V | V | ||||||||||
MMP-9 | V | V | ||||||||||
RANTES | V | V | V | V | ||||||||
EPO | V | V | V | V | V | V | ||||||
NT-4 | V | V | V | V | ||||||||
BDNF | V | V | ||||||||||
bFGF | V | V | ||||||||||
IGF-1 | V | V | V | V | ||||||||
VEGF | V | V | ||||||||||
VEGF-R1 | V | V | V | Λ | V | |||||||
VEGF-R2 | Λ | V | ||||||||||
PIGF | V | V | V | V | ||||||||
Ang-1 | V | |||||||||||
Ang-2 | V | V | V | V |
The inflammation-related protein is identified at the top of each set of columns, and the neurotrophic proteins are identified on the left. Λ indicates increased risk of a Z-score < −1 on the executive dysfunction assessment(s) identified just below the inflammation-related protein, while V indicates decreased risk. W indicates a DAS-II Working Memory Z-score ≤ −1, I indicates a NEPSY-II Inhibition-inhibition Z- score ≤ −1, S indicates a NEPSY-II Inhibition-Switching Z- score ≤ −1, and E indicates the executive dysfunction composite defined as a Z-score ≤ −1 on all three assessments.