Table 4.
Summary of Appendix Tables 10–17, which address two proteins at a time for the early epoch (4a) and separately for the late epoch (4b).a
| 4a. early epoch | ||||||||||||
| TNF-α | IL-8 | ICAM-1 | ||||||||||
| Proteins | W | I | S | E | W | I | S | E | W | I | S | E |
| IL-6R | V | V | V | V | V | V | ||||||
| MMP-9 | V | Λ | V | Λ | V | |||||||
| RANTES | V | V | V | V | V | V | ||||||
| EPO | Λ | Λ | Λ | Λ | ||||||||
| NT-4 | V | V | V | V | ||||||||
| BDNF | V | V | V | V | V | V | ||||||
| bFGF | Λ | V | V | V | V | |||||||
| IGF-1 | V | V | V | V | V | |||||||
| VEGF | V | V | V | V | V | V | V | V | ||||
| VEGF-R1 | V | V | V | V | V | V | V | V | ||||
| VEGF-R2 | V | V | V | V | V | |||||||
| PIGF | V | V | V | V | V | V | V | |||||
| Ang-1 | V | V | V | V | V | V | V | V | ||||
| Ang-2 | ||||||||||||
| 4b. late epoch | ||||||||||||
| TNF-α | IL-8 | ICAM-1 | ||||||||||
| Proteins | W | I | S | E | W | I | S | E | W | I | S | E |
| IL-6R | V | V | ||||||||||
| MMP-9 | V | V | ||||||||||
| RANTES | V | V | V | V | ||||||||
| EPO | V | V | V | V | V | V | ||||||
| NT-4 | V | V | V | V | ||||||||
| BDNF | V | V | ||||||||||
| bFGF | V | V | ||||||||||
| IGF-1 | V | V | V | V | ||||||||
| VEGF | V | V | ||||||||||
| VEGF-R1 | V | V | V | Λ | V | |||||||
| VEGF-R2 | Λ | V | ||||||||||
| PIGF | V | V | V | V | ||||||||
| Ang-1 | V | |||||||||||
| Ang-2 | V | V | V | V | ||||||||
The inflammation-related protein is identified at the top of each set of columns, and the neurotrophic proteins are identified on the left. Λ indicates increased risk of a Z-score < −1 on the executive dysfunction assessment(s) identified just below the inflammation-related protein, while V indicates decreased risk. W indicates a DAS-II Working Memory Z-score ≤ −1, I indicates a NEPSY-II Inhibition-inhibition Z- score ≤ −1, S indicates a NEPSY-II Inhibition-Switching Z- score ≤ −1, and E indicates the executive dysfunction composite defined as a Z-score ≤ −1 on all three assessments.