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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2018 Sep 5;14(2):173–187. doi: 10.1007/s11481-018-9808-3

Figure 5. Oral administration of aspirin increases the density of TH fibers in vivo in the striatum of C57/BL6 and A53T-Tg mice.

Figure 5.

Male C57/BL6 (A & B) and A53T-Tg (C & D) mice (n=5 per group) were treated with aspirin (2 mg/kg body wt/d) mixed in 0.5% methylcellulose orally via gavage. Control mice received 0.5% methylcellulose as vehicle. After 30 d of treatment, striatal sections were immunostained for TH (A, C57/BL6; C, A53T-Tg). Optical density of TH fibers was quantified in two striatal sections of each of five mice per group (B, C57/BL6; D, A53T-Tg). Results are mean ± SEM of five mice per group. *p<0.05 (= 0.03206) vs control (B); **p<0.01 (= 0.00124) vs control (D) by two-tailed paired t-tests.