Table 1.
Nanoparticles | cRGD (%) | Size (nm)a) | PDIa,b) | Zeta potential (mV)a) | Drug loading efficiencies (%)c) |
---|---|---|---|---|---|
Pt(IV) NPs | 0 | 148.8 ± 0.9 | 0.17 ± 0.02 | -5.97 ± 0.42 | 2.12 ± 0.14% |
Pt(IV) NP-0.25%cRGD | 0.25 | 149.6 ± 1.3 | 0.21 ± 0.01 | -6.17 ± 0.89 | 2.17 ± 0.21% |
Pt(IV) NP-0.5%cRGD | 0.5 | 153.7 ± 0.7 | 0.20 ± 0.02 | -5.93 ± 1.27 | 2.24 ± 0.17% |
Pt(IV) NP-cRGD | 1 | 151.1 ± 1.3 | 0.22 ± 0.01 | -5.27 ± 0.38 | 2.37 ± 0.11% |
Pt(IV) NP-2%cRGD | 2 | 158.1 ± 1.1 | 0.24 ± 0.03 | -5.42 ± 0.60 | 2.32 ± 0.25% |
a) Determined by DSL; b) Polydispersity; c) Determined by ICP-MS; Data were represented as mean ± SD (n = 3).