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. 2019 Jan 30;9(4):1047–1065. doi: 10.7150/thno.29820

Table 1.

Characterization of Pt(IV) NPs with different cRGD ligand densities.

Nanoparticles cRGD (%) Size (nm)a) PDIa,b) Zeta potential (mV)a) Drug loading efficiencies (%)c)
Pt(IV) NPs 0 148.8 ± 0.9 0.17 ± 0.02 -5.97 ± 0.42 2.12 ± 0.14%
Pt(IV) NP-0.25%cRGD 0.25 149.6 ± 1.3 0.21 ± 0.01 -6.17 ± 0.89 2.17 ± 0.21%
Pt(IV) NP-0.5%cRGD 0.5 153.7 ± 0.7 0.20 ± 0.02 -5.93 ± 1.27 2.24 ± 0.17%
Pt(IV) NP-cRGD 1 151.1 ± 1.3 0.22 ± 0.01 -5.27 ± 0.38 2.37 ± 0.11%
Pt(IV) NP-2%cRGD 2 158.1 ± 1.1 0.24 ± 0.03 -5.42 ± 0.60 2.32 ± 0.25%

a) Determined by DSL; b) Polydispersity; c) Determined by ICP-MS; Data were represented as mean ± SD (n = 3).