Skip to main content
. 2019 Jan 30;9(4):1029–1046. doi: 10.7150/thno.29868

Figure 2.

Figure 2

Behavioral tests to evaluate motor and neurological performance. The Kolmogorov-Smirnov test was performed to assess normality and resulting values were less than 5% of the critical values. n = 12 animals for each group. (A) Locomotor assessment as evaluated by elevated body swing test (EBST). Results were analyzed using one-way ANOVA for each time point (*p<0.05). Statistical analysis: ANOVA revealed significant treatment effects (EBST, F(4,67)=9.54, p<0.0001, Bonferonni's test p<0.05). (B) Motor coordination as revealed by rotarod test. Results were analyzed using one-way ANOVA for each time point. Statistical analysis: ANOVA revealed no significant treatment effects (p>0.05). (C) Neurological assessment as evaluated by forelimb akinesia test. Results were analyzed using one-way ANOVA for each time point (*p<0.05). Statistical analysis: ANOVA revealed significant treatment effects (FL, F(4,67)=9.885, p<0.0001, Bonferonni's test p<0.05). (D) Neurological assessment as evaluated by paw grasp test. Results were analyzed using one-way ANOVA for each time point (*p<0.05). Statistical analysis: ANOVA revealed significant treatment effects (PG, F(4,67)=10.42, p<0.0001, Bonferonni's test p<0.05).