FIG 3.

Distributions and pairwise associations of 16 host immune evasion genes. (A) Distribution of host immune evasion genes of 25 NAS species, arranged into five clades (A, B, C, D, and E) according to their placement in phylogenetic trees (32). Values and different colors within cells represent the percentage of isolates containing a given gene. The color gradient from red to dark green indicates increasing percentage of isolates containing the particular gene within species (light yellow, 1 to 25% of isolates; light blue, 26 to 50% of isolates; light green, 51 to 75% of isolates; dark green, 76 to 100% of isolates). (B) Pairwise associations of genes, computed using phi coefficients (143), with a color gradient representing the type of association (blue for positive; red for negative), while the intensity of the color and the size of the circle show the strength of the association.