FIG 6.

Absence of mutations in the V3 Env region associated with 10-1074 resistance. Amino acid alignment of HxB2 Env positions 301, 324 to 327, and 332 to 334 of SGS sequences from RNA extracted from circulating HIV at the initial detection of viremia in the plasma of untreated (n = 5 mice), 10-1074-treated (n = 4 mice), and 10-1074^null-treated OM5001 PHIR mice (n = 6 mice). These include the potential N-linked glycosylation sites at N301 and at N332 and the 324G(D/N)IR327 motif at the base of the V3 loop.