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Chemical structures of SSAs octreotide and octreotate. In octreotide, the C-terminal threonine (Thr) is reduced to the amino alcohol (yellow oval). Labeling moieties of all probes covered in this review are attached to the N-termini (red circles). In TOC and TATE, phenylalanine (Phe) of octreotide and octreotate (green ovals) are exchanged for tyrosine (Tyr). In NOC, Phe1 in octreotide (purple oval) is exchanged for naphthylalanine (Nal).
