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. 2019 Feb 7;9(5):1247–1263. doi: 10.7150/thno.29884

Figure 1.

Figure 1

Characterization of PSP and PSPS. ATM micrograph of (A) PSP and (B) PSPS. (C). Size distribution of PSP. (D). Thermostability of PSP. (E). Characterization of PSP by SEC-HPLC showing the molecular weight of PSP is 165.8 KD and it mainly exists as monomers. (F). Characterization of siRNA payload: gel shift assay of free siRNA, PSMAb, PSP, a mixture of PSMAb and FAM-siRNA (molar ratio: PSP/FAM-siRNA:1/1), and a mixture of PSP and FAM-siRNA (molar ratio: PSP/FAM-siRNA:1/1). (G). Characterization of siRNA release: gel shift assay of free siRNA, cell lysate, PSPS, and a mixture of PSPS and cell lysate. Scale bars = 20 nm. Representative results of 3 independent experiments are shown.