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. 2019 Feb 7;9(5):1247–1263. doi: 10.7150/thno.29884

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Inhibition of tumor growth in PC-3-PSMA+-xenografted mice by PSP-mediated delivery of TRIM24 siRNA. (A). Tumor growth of different PC-3-PSMA+ groups treated as indicated was observed using BLI every week after the first treatment. (B). Tumor volume analysis showing growth of PC-3-PSMA+ tumors after receiving indicated treatments. The arrows indicate the five treatments. (C). Digital pictures of resected tumors after receiving indicated treatments (D). Weight analysis of PC-3-PSMA+ tumors after receiving indicated treatments (E). Paraffin-embedded sections of resected PC-3-PSMA+ tumors from each group were stained with H&E. Data are shown as the mean ± S.E. (n=5). *P < 0.05, **P<0.01. Representative results of 3 independent experiments are shown.