Table 1.
Summary of craniofacial and tooth abnormalities in osteopetrosis patients from literature review.
| Abnormalities | ARO (cases, %) |
ADO (cases, %) |
Total (cases, %) |
|---|---|---|---|
| Tooth | 45/51 (88%) | 22/29 (76%) | 67/80 (84%) |
| Mandible | 33/51 (65%) | 9/29 (31%) | 42/80 (53%) |
| Middle of face and sinuses | 28/51 (55%) | 8/29 (28%) | 36/80 (45%) |
| Osteomyelitis | 24/51 (47%) | 10/29 (34%) | 34/80 (43%) |
| Fistulae | 13/51 (26%) | 6/29 (21%) | 19/80 (24%) |
| Calvarium | 32/51 (63%) | 9/29 (31%) | 41/80 (51%) |
| Frontal bossing | 28/51 (55%) | 6/29 (21%) | 34/80 (43%) |
| Shape and proportion of the facial skeleton | 38/51 (75%) | 13/29 (45%) | 51/80 (64%) |
| Hearing | 18/51 (35%) | 5/29 (17%) | 23/80 (29%) |
ARO: autosomal recessive osteopetrosis, ADO: autosomal dominant osteopetrosis.