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. 2019 Feb 26;10:153. doi: 10.3389/fphys.2019.00153

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Copyright © 2019 Dong, Zhang, Wen, Chen, He, Wang, Yin, Wu, Xue, Li, Fan and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NGAL was better associated with AKI-to-CKD progression. (A) The time course of changes in Scr levels and biomarker concentration after 45 min of UIRI. To create this plot, the level at the time point with the highest mean value was set to 100%, and the levels at all other time points were converted to a percentage of this maximum. (B) Correlations were analyzed between sNGAL and the extent of tubulointerstitial fibrosis (r = 0.87, P < 0.0001) and uNGAL and the extent of tubulointerstitial fibrosis (r = 0.93, P < 0.0001). sNGAL: serum NGAL, uNGAL: urinary NGAL.