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Effect of various processing parameters on the particle size (nm) and EE of YF4-LNPs. (A) The concentration of PLGA, (B) The volume of acetone, (C) The volume of the inner aqueous medium, (D) The pH, (E) The external water phase, (F) The concentration and (G) The volume of PVA, (H) The ultrasonic time of W1/O and (I)W1/O/W2, (J) The ratio of PLGA/LPs, and (K) The ultrasonic power.
