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The LSM1-7 complex participates in the decapping machinery. The LSM1-7 complex would interact with the oligo-A tract of mRNAs and through its interaction with the scaffold protein PAT1, it would recruit the DCP1, DCP2, VCS, DCP5 and SPI proteins, which, in turn, would remove the 5′CAP of mRNAs, allowing its subsequent 5′-3′ degradation by XRN4.
