Table 2.

Kinetic parameters obtained after fitting the release data from the MHASt-emulsions with LP and CT to different release models (mean ± standard deviation (SD), n = 6).

	Model	K	R2adjusted	AIC	T50% (min)	T90% (min)	DE24 h (% ± SD)
2.5%-MHASt-emulsion with LP	First order	0.05	0.723	55.3	14.3	47.5	38.4 ± 5.4
	Higuchi	14.68	0.731	38.3	12.0	39.0
	Korsmeyer–Peppas	25.63	0.973	25.6	56.3	2388.9
		n—0.18
	Weibull	α—3.14 β—0.20 Ti—0.53	0.972	26.3	83.9	12432.0
5%-MHASt-emulsion with LP	First order	0.01	0.838	30.4	111.1	369.1	8.1 ± 0.2
	Higuchi	2.53	0.960	16.6	390.1	1263.9
	Korsmeyer–Peppas	3.53	0.989	4.2	13,683.2	185,438.2
		n—0.39
	Weibull	α—27.17	0.985	5.1	148,476.5	1,028,8670.6
		β—0.35
		Ti—0.40
7.5%-MHASt-emulsion with LP	First order	0.00	0.273	24.5	182.2	605.1	5.3 ± 0.9
	Higuchi	1.63	0.871	13.1	979.1	3172.1
	Korsmeyer–Peppas	2.84	0.997	9.3	71,257.0	723,399.2
		n—0.27
	Weibull	α—31.79	0.996	11.7	902,911.8	39,677,378.5
		β—0.24
		Ti—0.40
2.5%-MHASt-emulsion with CT	First order	0.05	0.139	50.1	15.8	52.6	40.1 ± 8.3
	Higuchi	11.99	0.775	40.7	18.2	58.8
	Korsmeyer–Peppas	25.10	0.988	22.2	38.8	743.7
		n—0.20
	Weibull	α—3.31	0.974	28.3	283.7	2577.2
		β—0.21
		Ti—0.40
5%-MHASt-emulsion with CT	First order	0.02	0.886	31.6	43.8	145.7	17.9 ± 0.3
	Higuchi	5.65	0.981	18.3	78.4	254.0
	Korsmeyer–Peppas	5.60	0.988	14.4	85.8	291.9
		n—0.40
	Weibull	α—14.72	0.974	22.1	153.9	1015.0
		β—0.47
		Ti—0.42
7.5%-MHASt-emulsion with CT	First order	0.01	0.8693	25.6	94.5	313.8	9.3 ± 1.7
	Higuchi	2.91	0.9884	8.6	317.0	1027.2
	Korsmeyer–Peppas	2.50	0.9967	0.5	228.4	660.9
		n—0.49
	Weibull	α—33.44	0.9846	11.8	507.4	2717.3
		β—0.51
		Ti—0.40

K—release constant; R²_ajusted—adjusted coefficient of determination; AIC—Akaike Information Criterion; T50%—time required for 50% dissolution; T90%—time required for 90% dissolution; DE_{24 h}—dissolution efficiency at 24 h of release study; n—release exponent; α—scale parameter; β—shape parameter; Ti—location parameter.