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. 2019 Jan 7;11(1):83. doi: 10.3390/polym11010083

Figure 3.

Figure 3

Characterization of double-stranded oligonucleotide polyelectrolyte complex micelles. A discrepancy in length and shape is seen with dsDNA PCMs. PLys-PEG forms long flexible cylinders (A), while PVBTMA-PEG forms cylindrical or spheroidal PCMs with polydisperse lengths (B,C). (D) shows representative SAXS data for both systems with fitting results available in Table 1. Panel A is PLys(50)-PEG(5k) + 88 bp DNA, (B) is PVBTMA(194)-PEG(10k) + 10 bp DNA, and (C) is PVBTMA(24)-PEG(5k) + 88 bp. (A,C) negative-stain conventional EM and (B) is a cryo-EM micrograph. Scale bars = 50 nm unless noted.