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Immunohistochemistry results of PAPP-A2, IGFBP-5, IGF1R, and IGF1 in rat hip joints during different growth stage. P21 (n = 17), B7 (n = 12), and B14 (n = 12) represent day 1 before birth, day 7, and day 14 after birth, respectively. (a) (1, 2, and 3 original magnifications ×400; ①, ②, and ③ original magnification ×40). The black arrow indicates positive cells. A: acetabulum; F: femoral head. (b) PAPP-A2, IGFBP-5, IGF1R, and IGF1 in normal hip joints with time varying.
