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TNKS is Critical for Glycolytic Activity of Ovarian Cancer Cells. Cellular glucose uptake (a), lactate release (b), ATP levels (c), and O2 consumption rates (d) were measured in A2780 and OVCAR-3 cells after XAV939 treatment for 24 h or TNKS knockdown in the OVCAR-3 cells. XAV939, 10 μM. n = 3 for each group. Data were expressed as the mean ± SD. ∗, P < 0.05; ∗∗, P < 0.01.
