Table 1.
Summary of the performance (in PCC and AUC) of different prediction methods on the IEDB dataset
PCC | AUC | |||||||
---|---|---|---|---|---|---|---|---|
Length | 8 | 9 | 10 | 11 | 8 | 9 | 10 | 11 |
Alleles * | 38 | 118 | 63 | 37 | 38 | 118 | 63 | 37 |
allmer | 0.717 | 0.717 | 0.744 | 0.706 | 0.895 | 0.884 | 0.882 | 0.888 |
nmer | 0.524 | 0.702 | 0.672 | 0.488 | 0.775 | 0.875 | 0.845 | 0.775 |
Lmer | 0.664 | 0.702 | 0.699 | 0.670 | 0.871 | 0.875 | 0.860 | 0.868 |
*For each length, only alleles with >20 data points and >3 binders are considered for validation.
allmer is the method trained on peptides of all lengths; nmer refers to networks trained only on peptides of length n; L-mer refers to networks trained on 9-mers and applied to peptides of different length using the L-mer approximation. Note that the L-mer approximation for 9mer reduces to the nmer method.