Table 4.
Proportion of nonadherence and factors explaining nonadherence to the ACTs
| Nonadherence N=27 | Univariate | Multivariable | |||
|---|---|---|---|---|---|
| OR (95% CI) | P-value | Adj OR (95% CI) | |||
| Gendera | |||||
| Female | 10 (9.8) | 1 | |||
| Male | 17 (18.9) | 2.12 (0.92–5.12) | 0.07 | ||
| Agea | |||||
| 5 years and above | 7 (14.6) | 1 | |||
| Under 5 years | 20 (13.9) | 0.93 (0.38–2.56) | 0.90 | ||
| Easy affordability of ACTa | |||||
| Yes | 23 (19.0) | 1 | |||
| No | 4 (5.6) | 0.26 (0.07–0.70) | 0.010 | ||
| Blood sample takena | |||||
| Yes | 19 (11.8) | 1 | 1 | ||
| No | 8 (25.8) | 2.60 (0.98–6.56) | 0.050 | 1.49 (0.55–4.03) | 0.14 |
| Received advices from HCWa | |||||
| Yes | 6 (7.8) | 1 | 1 | ||
| No | 21 (18.3) | 2.59 (1.04–7.47) | 0.041 | 3.21 (1.13–9.12) | 0.019 |
| First dose of ACT taken at HFa | |||||
| Yes | 13 (10.8) | 1 | |||
| No | 14 (19.4) | 1.98 (0.86–4.57) | 0.10 | ||
| Number of ACT tabletsb | 6.0 (3.0–24.0) | 1.04 (0.97–1.11) | 0.19 | ||
| Number of CMb | 2.0 (0.0–4.0) | 1.03 (0.61–1.72) | 0.92 | ||
| Fever after treatmenta | |||||
| No | 24 (13.8) | 1 | |||
| Yes | 3 (16.7) | 1.29 (0.27–4.36) | 0.72 | ||
| Side effects of ACTa | |||||
| No | 9 (10.3) | 1 | |||
| Yes | 18 (17.1) | 1.77 (0.76–4.40) | 0.18 | ||
Notes:
a
Represents data presented in number (%);
b
represents data presented in median (minimum–maximum). Statistically significant values are shown in bold (P<0.05).
Abbreviations: Adj, adjusted; ACT, artemisinin-based combination therapy; CM, concomitant medication; HCW, health care worker; HF, health facility.