Fig. 4.

VPO1 induces cardiac fibroblasts differentiation and proliferation in vivo. (A) VPO1, α-SMA and Collagen I protein levels in heart tissues of mice injected with siRNA were assessed by western blot and quantified by Image Lab. n = 6. (B). Representative images of immunostaining of Ki67 staining in mouse hearts subjected to MI and injected with si-NC and si-VPO1. Quantification of Ki67 positive cells in each group. n = 6. Data are presented as mean ± SEM. One-way ANOVA test was used for A-B. *P < 0.05, **P < 0.01.